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The U.S. biomarkers market reached a valuation of USD 25.92 billion in 2024, with a projected CAGR of 15.16% from 2025 to 2034, reflecting robust growth across multiple market segments. Biomarkers are broadly categorized by type, including genomic, proteomic, and metabolomic markers, each playing a critical role in disease diagnosis, prognosis, and therapeutic monitoring. Among these, genomic biomarkers dominate the market, driven by advancements in next-generation sequencing (NGS), the rising adoption of liquid biopsies, and the increasing use of companion diagnostics in oncology. Proteomic biomarkers are also gaining traction, particularly in autoimmune and cardiovascular disease applications, where protein expression profiling offers high specificity and actionable insights for clinicians.
From an application standpoint, oncology remains the largest end-use segment, accounting for over 40% of total biomarker adoption in 2024. This is attributed to the growing emphasis on personalized cancer therapies, the expansion of immuno-oncology research, and the increasing number of FDA-approved biomarker-based companion diagnostics. Neurological and cardiovascular applications are emerging as high-growth areas, supported by rising prevalence of Alzheimer’s disease, Parkinson’s disease, and heart failure, alongside growing investments in biomarker discovery programs. Segment-wise performance is also being influenced by end-user industries, with pharmaceutical and biotechnology companies leading in biomarker utilization for drug development, followed by academic research institutions and diagnostic laboratories.
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• Qiagen N.V.
• Agilent Technologies, Inc.
• Bio-Rad Laboratories, Inc.
• PerkinElmer Inc.
• Danaher Corporation
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